Peng's research demonstrated that 70 mg/kg baicalin had a significant effect on CCl4-induced liver fibrosis, which was correlated with immunoregulation of the imbalance between profibrotic and anti-fibrotic cytokines, including TGF-β1, TNF-α, IL-6, and IL-10 expression [45]. This evidence concerns the gene TGFB1 and Hepatic fibrosis.