Additionally, nearly 20% of individuals with TUBB2B tubulinopathy seem to have normal motor function, which is in line with previous reports of a low prevalence of muscular tone abnormalities in TUBB2B tubulinopathy.4 Diagnostic delay in TUBB2B tubulinopathy could be partially explained by the more subtle clinical signs at disease onset. The gene discussed is TUBB2B; the disease is tubulinopathy.