HOXA4 is a homeobox gene that encodes a transcription factor involved in development, and it has previously been reported as hypermethylated in CLL23 and is associated with imatinib resistance among chronic myeloid leukaemia patients.24SLCO3A1 encodes an anion transporter that may be implicated in drug uptake. This evidence concerns the gene HOXA4 and chronic myelogenous leukemia, BCR-ABL1 positive.