To find the valuable molecular marker between CTCs and tumor-derived exosomes that was affected in metastasis after online analysis of the total similarity of their expressed genes, the following 15 genes were found: TLN1, TMEM51, GNPNAT1, RPS4X, MARCKSL1, FARP1, RHOB, HSP90AB1, LFNG, AHNAK, RPSA, CNPY2, PRDX1, SLC25A5, and TGFBI, as shown in Fig. 1. This evidence concerns the gene CNPY2 and neoplasm.