CpGs near other AD-related genes, like Tshz3 [64], Rapgefl1 [65, 66], Exoc3l2 [67, 68], Dapk1 [69], Apoe [70] and Hpcal1 [71] were differentially methylated between B6 and AD mice. The gene discussed is APOE; the disease is Alzheimer disease.