Many published studies verified the distribution of Gal-9 protein among various malignant tissues, such as NSCLC, hematological malignancy, prostate cancer, as well as skin cancer.19 38 47 48 In spite of a considerable amount of studies focusing on the Gal-9 protein expression in cancer, few comprehensive data were available in SCLC. The gene discussed is LGALS9; the disease is prostate cancer.