Specifically, we investigated the single cell abundance of eleven MOIs (Additional file 1: Table S1) across microglial and perivascular macrophage populations in immunohistochemically stained normal and AD cortex; CD45, HLA-DR, CD14, CD74, CD33, CD206, CD32, CD163, P2RY12, TMEM119, and L-Ferritin. This evidence concerns the gene CD33 and Alzheimer disease.