Of the seven MOIs with an increase in the Iba1low population in AD, the mean population intensity of CD45, HLA-DR, CD14, CD74, and CD32 was significantly higher in the Iba1low MOIhigh population relative to the Iba1high MOIhigh population in both normal and AD, suggesting that cells with the highest MOI expression were those with low Iba1 (Fig. 4A–D, G). The gene discussed is PTPRC; the disease is Alzheimer disease.