When quantified, the most notable change in the abundances of the Iba1-MOI populations identified was a significant increase in the proportion of the Iba1low MOIhigh population for seven of the 11 MOIs in AD (Fig. 3): CD45, HLA-DR, CD14, CD74, CD33, CD32, and L-Ferritin. Here, AIF1 is linked to Alzheimer disease.