In another study, the relationship between SOD activity and thiobarbituric acid reactive substances in the platelets of 36 schizophrenia patients (aged 18–36) was examined in comparison to 32 healthy controls; lower antioxidative processes were observed in schizophrenia patients as well as an imbalance between prooxidants and antioxidants [115]. This evidence concerns the gene SOD1 and schizophrenia.