Furthermore, the authors chose to compare two different scoring methods to evaluate the PD-L1 IHC assay: the tumor proportion score (TPS), which is the percentage of viable tumor cells showing partial or complete membrane staining at any intensity, and the combined positive score (CPS), the number of PD-L1 staining cells (tumor cells, lymphocytes and macrophages) divided by the total number of viable tumor cells, multiplied by 100 [108]. The gene discussed is CD274; the disease is neoplasm.