Mouse/human chimeric IgE (MOv18) specific for the ovarian cancer antigen, folate receptor alpha (FRα)-mediated ADCC and ADCP of ovarian cancer cells (IGROV1) by human peripheral blood mononuclear cells (PBMCs) [29], human monocytic U937 cells [30] and peripheral blood monocytes and eosinophils [42]. This evidence concerns the gene IGHE and ovarian cancer.