Besides, MAO-B catalyzes breakdown of 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine (MPTP) to 1-methyl-4-phenylpyridinium ion (MPP+), which is a neurotoxic metabolite that can induce Parkinsonism in experimental animal models [16]. Here, MAOB is linked to Parkinson disease.