Specifically, here we will discuss (a) the role of MYC in promoting metastasis through the regulation of EMT, (b) how MYC participates in the different steps of the metastatic cascade, (c) the importance of non-coding RNAs in MYC-induced metastasis as well as (d) the impact of MYC in shaping the tumor metastasis microenvironment. Here, MYC is linked to neoplasm.