However, serum MIC-1 from African American prostate cancer patients (median = 1,393.9 pg/mL, range = 512.2 to 8,682.5) was significantly higher as compared to African American healthy donors (median = 865.7 pg/mL, range = 329.1, 1667.1; p < 0.001) (Figure 1). This evidence concerns the gene GDF15 and prostate cancer.