Drug classes known to induce treatment-associated hypertension include the anti-microtubule agents (paclitaxel, docetaxel, cabazitaxel), alkylating agents (cisplatin, cyclophosphamide and ifosfamide derivatives), vinca alkaloids (vincristine), mammalian target of rapamycin mTOR inhibitors, androgen receptor antagonists (abiraterone) and interferon-alpha. This evidence concerns the gene MTOR and hypertensive disorder.