It is known that lymphoma cells are diffusely positive for CD3 and TCR γ, mostly positive for granzyme-B and TIA-1, variably positive for CD7, CD8, and CD30, and negative for CD4 and TCR β.[27] In some cases, when CD7 is strongly positive, the diagnosis of lymphoma needs to be ruled out. The gene discussed is CD4; the disease is lymphoma.