SSX2 and synovial sarcoma: Since >90% of SS has t (x; 18) (p11; q11) chromosome translocations, resulting in the fusion of genes SS18-SSX1 or SS18-SSX2,[15] histopathological HE and immunohistochemical staining are very effective in the diagnosis of PRSS.[16] However, a combination of cytogenetic or molecular genetic techniques may improve diagnostic accuracy.