Mining single nuclei RNA-seq sequencing data (Hodge et al., 2019) revealed that SRPK1 and SRPK2 are broadly expressed in human cortical neurons, while SRPK3 is specifically expressed in two GABAergic inhibitory neuron populations (Figure 6G), which have been implicated in intellectual disability (Sgadò et al., 2011; Smith-Hicks, 2013). Here, SRPK1 is linked to Intellectual disability.