We have previously demonstrated NFATc1 messenger RNA (mRNA) induction in peripheral blood mononuclear cells (PBMCs) in pediatric asthma and that the absence of NFATc1 in T cells results in the downregulation of IL‐4 and other Th2 cytokines and IgE in asthma models.2, 3, 4. The gene discussed is IGHE; the disease is asthma.