Furthermore, human SRCIN1-flanking regions contain several genes involved in tumor initiation and progression, such as ERBB2 (17q12), BRCA1 (17q21), retinoic acid receptor-α (RARA; 17q21) and signal transducer and activator of transcription 3 (STAT3; 17q21). Here, STAT3 is linked to neoplasm.