We found increased ADAMTS-13 levels (mean 342.4 ng/mL) in LF patients compared with HCs (mean 165.5 ng/mL; p<0.0292) (Figure 2, panel D), suggesting high molecular weight vWF multimers also might be decreased, especially in the microvasculature where shear stress enhances the availability of vWF cleavage sites. The gene discussed is VWF; the disease is Lassa fever.