We found increased ADAMTS-13 levels (mean 342.4 ng/mL) in LF patients compared with HCs (mean 165.5 ng/mL; p<0.0292) (Figure 2, panel D), suggesting high molecular weight vWF multimers also might be decreased, especially in the microvasculature where shear stress enhances the availability of vWF cleavage sites. This evidence concerns the gene ADAMTS13 and Lassa fever.