As shown in Figure 1F‐H, the cancerous tissues originating from the tumour xenograft models injected subcutaneously with A549‐ZNF300‐NC and A549/DDP‐shZNF300 cells presented a remarkable shrinkage in the tumour weight and volume when compared to that injected with A549‐ZNF300 and A549/DDP‐shZNF300‐NC cells after cisplatin was applied. This evidence concerns the gene ZNF300 and neoplasm.