Heterogeneous nuclear ribonucleoprotein; modifies TDP43 [148,149]; associated with DDR [150]; hnRNP L recruits 53BP1 and BRCA1 in cancer [151]; hnRNP F,H, and K are related to ALS [152] and p53 recruitment [153]. The gene discussed is BRCA1; the disease is amyotrophic lateral sclerosis.