In direct comparisons of effect sizes from analyses of each type of genetic variant, FMRP targets annotated by overrepresented functional terms were not more enriched for association with schizophrenia than unannotated FMRP targets (common variants: P = 0.081; rare loss-of-function variants: P = 0.25; rare nonsynonymous variants: P = 0.47; de novo nonsynonymous variants: P = 0.39; de novo loss-of-function variants: P = 0.80). This evidence concerns the gene FMR1 and schizophrenia.