Indeed, our TB incidence rates of 22.5/100 PYs with 95% CI of (11.2–45.0) in PLWH with < 50 CD4 T cells/μl, are far higher than those of 4.2/100 PYs with 95% CI (1.4–12.7) found in a cohort of PLWH in Nigeria with similar CD4 T cell values [40]. This evidence concerns the gene CD4 and tuberculosis.