With respect to CDKN1C variants and intrauterine growth retardation, the current literature reports now a total of 12 cases with IMAGe syndrome and adrenal insufficiency, comprehensively summarized by Suntharalingham et al. [26], 4 cases with SRS ([4, 5, 14], and this study) and a single case with an undefined short stature syndrome with early manifestation of diabetes mellitus [6]. Here, CDKN1C is linked to diabetes mellitus.