BCL2 and leukemia: Because leukemia-initiating cells have been shown to aberrantly overexpress BCL2 and be preferentially killed by BCL2 inhibition, even when in a quiescent state [17, 18], we sought to characterize the effects of midostaurin plus venetoclax on blast re-plating potential using methylcellulose colony-forming unit (CFU) assays of primary patient cells.