On the other hand, the tumor suppressor role of miR-342-3p via inhibition of cell proliferation, migration and invasion has been demonstrated in colon, lung, breast and hepatocellular carcinoma, by downregulation of oncogenic targets, including FOXQ1, DNMT1, MYC and IKK-γ [25–29]. The gene discussed is DNMT1; the disease is neoplasm.