Moreover, the tumor-suppressive role of miR-342-3p in B cell lymphoma was mediated by inhibition of pro-survival autophagy via direct targeting of MAP1LC3B, a precursor of LC3-II, hence a functional marker of autophagy, in addition to targeting and repression of DNMT1, with consequent hypomethylation and re-expression of tumor suppressor genes. This evidence concerns the gene DNMT1 and neoplasm.