Over the last few years, genome-wide analysis revealed numerous alterations in ovarian cancer genomes including the inactivation of mutations in tumor suppressor genes such as TP53, BRCA1, BRCA2, PTEN, and RB1; and in a SWI/SNF chromatin remodeling gene, ARID1A [102, 103]. The gene discussed is TP53; the disease is ovarian cancer.