In accordance, we found the eosinophil marker genes RNASE2 (ribonuclease A family member 2), RNASE3, SIGLEC8 (sialic acid binding Ig-like lectin 8) and IL5RA [29] as well as PRSS33 (serine protease 33) [58] being exclusively expressed in eosinophils in the deconvolved asthma data (see Additional file 10). Here, RNASE3 is linked to asthma.