The analysis of variance revealed that rheumatic diseases did not affect the galectin-3 concentration (H = 0.395, p = 0.821), CRP (H = 4.798, p = 0.091), PLT (H = 5.061, p = 0.080), and HGB (H = 3.935, p = 0.140), but effect the ESR (H = 13.001, p = 0.002). This evidence concerns the gene LGALS3 and rheumatic disorder.