In this study, we examined the associations between polymorphisms in GP6 (rs1671152), PEAR1A (rs12566888), MRVI1 (rs7940646), PIK3CG (rs342286), JMJD1C (rs10761741), and SHH (rs2363910) and unstable angina. The gene discussed is IRAG1; the disease is angina pectoris.