The aim of this study was to examine the associations between polymorphisms in GP6 (rs1671152), PEAR1A (rs12566888), MRVI1 (rs7940646), PIK3CG (rs342286), JMJD1C (rs10761741), and SHH (rs2363910) and CAD in the form of unstable angina, as well as to study selected clinical and biochemical parameters. Here, GP6 is linked to angina unstable.