RMRP and cartilage-hair hypoplasia: In the attempt to find a potential causative relationship between the different functions of RMRP and CHH development, it has been reported that RMRP is expressed during the hypertrophic phase of chondrocyte differentiation in mice, and that the trans-differentiation in the chondrocytes from CHH patients’ fibroblasts is impaired in comparison with control fibroblasts.