Thereby, we compared SOX9 gene expression in healthy cartilage (26 samples) with the expression in grade I (G1) chondrosarcoma (17 samples), grade II (G2) chondrosarcoma (39 samples), grade III (G3) chondrosarcoma (17 samples) and dedifferentiated chondrosarcoma (16 samples). This evidence concerns the gene SOX9 and chondrosarcoma.