Performing a meta-analysis of intrinsic gene expression levels of SOX9 in human chondrosarcoma biopsies, revealed an increase in SOX9 in grade I (G1), II (G2) and III (G3) tumors compared to cartilage, but interestingly no significant difference between dedifferentiated chondrosarcoma (DDCS) and cartilage was found. Here, SOX9 is linked to chondrosarcoma.