Altogether our data suggest that murine macrophages and to a lesser extent DC maynot be able to process and present IMYNYPTM, or presentit less efficiently, thus explaining the inefficient priming and expansion ofTB10.44−11-specific CD8 T cells following 667 orErd.EsxHA10T infection and the inefficient recognition ofmacrophages infected with 667. This evidence concerns the gene CD8A and infection.