CD4 and infection: Interestingly, levels of naïve and stem cell memory CD4+ T cells was positively correlated with infection of plasma cells (Fig 5B and Fig 5C, left panels) with a greater effect on CD20+ plasma cells than CD20- plasma cells, while overall levels of CD45RO+ activated memory T cells were negatively correlated with KSHV infection of plasma cells (Fig 5C, right panel).