In this study we analyzed the Olink® Oncology II and Inflammation panels (in total 177 unique protein biomarkers) in 180 women with benign tumor, borderline tumor, early (stage I) or late (stage II-IV) EOC, with the aim of searching for new candidate biomarkers with the potential to improve the performance of HE4 and CA125 for discrimination between benign disease and EOC. The gene discussed is WFDC2; the disease is benign neoplasm.