In univariable analysis, age at admission, weight, chronic respiratory failure, respiratory rate ≥ 24, SpO2 on room air, Oxygen therapy on admission, SpO2 on oxygen, dyspnea, myalgia, WHO clinical scale, neutrophils, eosinophils, lymphocytes, platelets, CRP level, IL-6 level, procalcitonin, serum ferritin, high-sensitivity cardiac troponin T, D-dimer, and chest CT-scan were associated with WHO scale ≥ 5 within day 14. This evidence concerns the gene CRP and respiratory failure.