SNP rs7087063 in gene CELF2 on chromosome 10 was found to be associated with the HMM estimated activity variability during wake (p-value = 3.0×10−8), and we note that CELF2 was previously found to be associated with Alzheimer’s disease [24] (Table 1). Here, CELF2 is linked to early-onset autosomal dominant Alzheimer disease.