For the strength of 1-day periodicity, five circadian SNPs were identified: rs189005747 at gene XKR4 (p-value = 9.9×10−9), rs534035399 at LINC01508 (p-value = 1.8×10−9), rs144874087 near LINC01935 (p-value = 1.9×10−8), rs181820530 near LINC01935 (p-value = 4.5×10−8), and rs554696049 at LINC01501 (p-value = 4.8×10−8), in which XKR4 was previously found to be associated with thyroid stimulating hormone [40–42] and coronary artery disease, and LINC01508 and LINC01501 are RNA genes (shown in S2 Table). Here, LINC01508 is linked to coronary artery disorder.