We next assessed whether the phenotype of the gemR models acquired in vivo differed from drug-sensitive counterparts with respect to expression of proteins involved in gemcitabine transport into tumor cells (hCNT1 and hENT1) or in gemcitabine metabolism (RRM1, RRM2, CDA, dCK) [Figure 3]. This evidence concerns the gene SLC29A1 and neoplasm.