BTD and sickle cell disease: The following diseases have been identified: 653 Congenital Hypothyroidism cases (1:2075), 101 Congenital Adrenal Hyperplasia (1:8743), 75 Biotinidase Deficiency ((1:8142), 284 Amino Acid, Organic Acid and Fatty Acid cases (MS/MS) (1:2377), 86 Phenylketonuria (PKU) (1:14,523), 429 sickle cell diseases (0.44/1000), 9319 sickle cell traits (7.8/1000), 77 β–thalassemia diseases, 12 Galactosemia (1:12,925) and 1145 Glucose-6-Phosphate Dehydrogenase Deficiency cases.