The National Neonatal Screening Program in United Arab Emirates was launched in January 1995 and covered the following diseases at the national level: Phenyl ketonuria (1995), Congenital hypothyroidism (1998), Sickle cell disease (2002), Congenital Adrenal Hyperplasia (2005), Biotinidase Deficiency (2010), Tandem mass spectrometry (MS/MS) for AA, FA&OA (2011), Galactosemia (2016) & G6PD deficiency (2019). This evidence concerns the gene BTD and sickle cell disease.