Moreover, it has been shown that the use of probiotics in T1D adults was associated with a better glycemic control, reduced TLR4 inflammatory signaling, and also increased synthesis of glucagon-like peptide-1 (GLP-1), which is a hormone that stimulates the secretion of pancreatic beta cells leading to a decrease in blood sugar levels (132, 133). This evidence concerns the gene TLR4 and type 1 diabetes mellitus.