Furthermore, a significant difference in SAS was found in RA patients with hsa_circ_0003353 (Wald Chi-square value = 4.628, potence ratio: 2.753, P = 0.034), MAPKAPK5-AS1 (Wald Chi-square value = 3.572, potence ratio: 1.563, P = 0.047), indicating that these are risk factors for SAS. Here, MAPKAPK5 is linked to SATB2 associated disorder.