Overexpression of CAP1 may have significant clinical implications as a diagnostic/prognostic factor for lung cancer (Tan et al., 2013), esophageal squamous cell carcinoma (Li et al., 2013), epithelial ovarian cancer (Hua et al., 2015) and glioma (Bao et al., 2016; Fan et al., 2016). Here, CAP1 is linked to central nervous system cancer.