SLITRK3 (SLIT And NTRK Like Family Member 3) is expressed predominantly in neural tissues with neurite-modulating activity (Aruga et al., 2003), in hematopoietic stem cells and leukemias (Milde et al., 2007), and correlates to gastrointestinal stromal tumor risk rating and prognosis (Wang et al., 2015). The gene discussed is SLITRK3; the disease is leukemia.