Tumor cells can induce the phosphorylation of hormone-sensitive lipase and activate lipolysis in BMAT, allowing the transfer of fatty acids from adipocytes to tumor cells in AML (Shafat et al., 2017; Tabe et al., 2020), multiple myeloma (Morris et al., 2020), and prostate tumor (Herroon et al., 2019). The gene discussed is LIPE; the disease is neoplasm.