Curcumin, the main active component of curry spices, and curcuminoid from Curcuma longa plants have been reported to induce autophagy in AD mice limiting mTOR/Akt signaling and sustaining LC3 (Wang C. et al., 2014; Shakeri et al., 2019; Voulgaropoulou et al., 2019). This evidence concerns the gene MAP1LC3A and Alzheimer disease.