This list covered all HSP genes (SPGs) known at the time of study including 65 HSP genes (SPG1 – SPG80; SPGs with defined chromosomal loci but unknown genes could not be analyzed), 30 ALS-related genes, 18 SMA-related genes and 55 spasticity-related genes. Here, UBAP1 is linked to amyotrophic lateral sclerosis.