Mesothelioma stem cells (MSCs) might be responsible for tumor repopulation after chemoradiation in murine mesothelioma (102), and cisplatin-resistant, CSC-like subpopulations could be enriched by aldehyde dehydrogenase (ALDH)high and CD44+ in mesothelioma cell lines (103). This evidence concerns the gene CD44 and mesothelioma.