SRSF3-mediated alternative splicing was also reported to be associated with many other key genes, such as CD19 (132), CD44 (68, 133), and VEGF (78), and to be involved in other tumor related biology process, including the resistance to CART-19 immunotherapy (132), tumor cell homeostasis (21), tumor microenvironment (low pH) (78), and the maintenance of HPV-related cancer (134). Here, CD44 is linked to neoplasm.