Global pathway analysis (Enrichr) suggests that networks that mediate the immune response (Macrophage Markers, Inflammatory Response Pathway) are enriched in cell clusters more abundant at week 8, while genes associated with tumor-promoting pathways (MAPK signaling pathway, EGFR signaling pathway, TGFβ Signaling Pathway) are enriched at week 16 (Supplementary Table 5). The gene discussed is EGFR; the disease is neoplasm.